A UGA research team has received funding from the U.S. Environmental Protection Agency to take a close look at something 100,000 times smaller than the width of a hair that offers great promise for major advances in medicine, manufacturing, electronics and other areas of science.
The $364,000 three-year project will examine zinc oxide nanoparticles, particularly their availability, their behavior in the food chain and any toxic effects they might have.
Manufactured zinc oxide nanoparticles are one of the most diverse classes of manufactured nanoparticles. The field of nanotechnology uses nanoparticles (small molecules) for industrial applications in many fields including medicine, electronics, manufacturing, energy production, pollution control, and environmental remediation.Though the nanotechnology revolution may offer major advances, the potential negative impacts to the environment and human health are unknown. Understanding the potential environmental impacts of manufactured nanoparticles is critical because the number of nanoparticle-based products is expected to increase dramatically over the next several decades.
“The focus of our proposal is to examine the uptake and toxicity of zinc oxide nanoparticles to microorganisms and small worms called nematodes that are commonly found in soil,” says Paul Bertsch of UGA’s Department of Crop and Soil Sciences and Savannah River Ecology Lab, who is the principal investigator on the interdisciplinary project.
“We also want to see if nematodes feeding on pre-exposed microorganisms bioaccumulate more or less zinc oxide compared to direct exposure,” Bertsch says. “This will provide an indication if food chain transfer is an important process for manufactured nanoparticles, which may begin to establish the potential ecological and human health risks of nanoparticles released into the environment.”
Currently there is little information on the bioavailability and toxicity of nanoparticles, although previous work by SREL researchers provided evidence that an aluminum oxyhydroxide nanocluster is far more toxic to plants than the aluminum ion.
“This was a surprising finding,” says Bertsch, “and one that makes the outcome of the new work uncertain and exciting.”
Other members of the research team include Travis Glenn and Andrew Neal from SREL, Phil Williams from the College of Public Health and Brian Jackson from Dartmouth College.
The researchers will conduct the work at SREL and at UGA and use advanced X-ray microprobes at the National Synchrotron Light Source (Brookhaven National Lab) and at the Advanced Photon Source (Argonne National Lab).
